Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromopyridine → 2-fluoro-N-(2-pyridyl)acetanilide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromopyridine | HCID 7973 | — |
| 반응물 | 2-Fluoro-N-phenylacetamide | HCID 9504 | — |
| 생성물 | 2-fluoro-N-(2-pyridyl)acetanilide | HCID 21993511 | 75.2% |
반응 단계
Using 2-fluoroacetanilide (4.6 g) and 2-bromopyridine (9.5 g), a reaction was made in the same manner as in 1) of Production Example 14. The subsequent purification by silica gel column chromatography (developing solvent, ethyl acetate:hexane=1:1.5) produced 2-fluoro-N-(2-pyridyl)acetanilide (5.2 g, crude product) as a red oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06235730B1 |
| 출처 데이터셋 | uspto-grants-2001_05 |
| ORD ID | ord-742831b86bf34a6ca0b650a7d420922f |
| 출처 메모 | uspto-grants-2001_05 |