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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1977885생성일: 2026년 10월 27일

4-(4-Methylpiperazin-1-yl)butan-1-amine → 5-{3-[4-(4-Methyl-piperazin-1-yl)-butyl]-ureido}-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazole-4-carboxylic acid amide

https://huagongshe.com/reaction/1977885

반응식

참여 물질

역할이름HCID투입량
반응물4-(4-Methylpiperazin-1-yl)butan-1-amineHCID 6484192—
반응물[4-Carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl esterHCID 54053016—
생성물5-{3-[4-(4-Methyl-piperazin-1-yl)-butyl]-ureido}-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazole-4-carboxylic acid amideHCID 10052189—

반응 단계

The title compound was prepared from [4-carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl ester and 4-(4-methyl-piperazin-1-yl)-butylamine by the procedure analogous to Example 1. MS (APCI, m/z): 515 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06235764B1
출처 데이터셋uspto-grants-2001_05
ORD IDord-43a6ff8ee02b4b26b20c86e77a1754ec
출처 메모uspto-grants-2001_05