5,7-Dimethyladamantane-1,3-diol → 1,3-Dimethyl-5-hydroxy-7-acryloyloxyadamantane

반응식

[C:1](OCC12CC3CC(CC(O)(C3)C1)C2)(=[O:4])[CH:2]=[CH2:3].[CH3:18][C:19]12[CH2:29][C:23]3([OH:30])[CH2:24][C:25]([OH:28])([CH2:27][C:21]([CH3:31])([CH2:22]3)[CH2:20]1)[CH2:26]2>>[CH3:31][C:21]12[CH2:27][C:25]3([OH:28])[CH2:24][C:23]([O:30][C:1](=[O:4])[CH:2]=[CH2:3])([CH2:29][C:19]([CH3:18])([CH2:26]3)[CH2:20]1)[CH2:22]2

참가 물질

반응물 2

HCID 5806055,7-Dimethyladamantane-1,3-diol

HCID 219967831-Hydroxy-3-(acryloyloxymethyl)adamantane

생성물 1

HCID 222287881,3-Dimethyl-5-hydroxy-7-acryloyloxyadamantane수율 87%

실험 절차

The reaction was conducted in the same manner as the step of Example 36 (2) except that 1,3-dimethyl-5,7-dihydroxyadamantane was used instead of the 1,3-dicarboxy-5-adamantanol, and, as a result, a 1,3-dimethyl-5-hydroxy-7-acryloyloxyadamantane (yield: 87%, white solid) was obtained.

출처 및 근거

ORD 기록: ord-6c67c3a798b54d3a8126d39f48f5fced
출처 데이터셋: uspto-grants-2001_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06235851B1

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