Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl cyanoacetate → Ethyl 2-cyano-3-hydroxy-4,4,5,5,5-pentafluoro-2-pentenoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl cyanoacetate | HCID 7764 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Perfluoropropionyl chloride | HCID 67911 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Ethyl 2-cyano-3-hydroxy-4,4,5,5,5-pentafluoro-2-pentenoate | HCID 86756713 | — |
반응 단계
To 20 ml of tetrahydrofuran, 3.39 g (30 mmol) of ethyl cyanoacetate and 6.06 g (60 mmol) of triethylamine were dissolved and stirred at room temperature. Successively, 5.47 g (30 mmol) of pentafluoropropionyl chloride was dropwise added and stirred for 5 hours at room temperature. However, formation of desired product could not be confirmed.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06235911B1 |
| 출처 데이터셋 | uspto-grants-2001_05 |
| ORD ID | ord-5ebf959e1e1d4832bd243770b69d9c26 |
| 출처 메모 | uspto-grants-2001_05 |