Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pentafluoroaniline → 4-(Pentafluorophenyl)-1-carbethoxysemicarbazide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pentafluoroaniline | HCID 13040 | — |
| 반응물 | Ethyl 3-(chloroformyl)carbazate | HCID 84905 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 4-(Pentafluorophenyl)-1-carbethoxysemicarbazide | HCID 12904376 | — |
반응 단계
Pentafluoroaniline (17 g, 0.106 mol) is dissolved in 300 ml of toluene with heating. The 2-carbethoxyhydrazinecarbonyl chloride, 19.4 g (0.122M) is added to the hot solution. The mixture is refluxed until a white solid precipitates. The solid is filtered to give 24.8 g. The product is crystallized by dissolving in ethyl acetate/toluene (1/2 by vol) and evaporating until crystals appear, mp 180°-182°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04481356 |
| 출처 데이터셋 | uspto-grants-1984_11 |
| ORD ID | ord-fc14ebfe1bdf48c483d8b453f2ba1ec2 |
| 출처 메모 | uspto-grants-1984_11 |