Dichloromethane → HCID 12962282, 화합물

HRID 1979875노트

반응식

HRID 1979875 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]2[NH:14][CH2:13][CH2:12][O:11]2)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].C(Cl)Cl.[Cl:18][CH:19]([Cl:23])[C:20](Cl)=[O:21]>C(N(CC)CC)C>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]2[N:14]([C:20](=[O:21])[CH:19]([Cl:23])[Cl:18])[CH2:13][CH2:12][O:11]2)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]

참가 물질

5

반응물 3

HCID 6344DichloromethaneHCID 6593Dichloroacetyl chlorideHCID 2417432-(3-Nitrophenyl)-1,3-oxazolidine

생성물 1

HCID 12962282HCID 12962282, 화합물

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

Five and eight tenths (5.8) grams of 2-m-nitrophenyl oxazolidine was dissolved in 50 ml. methylene chloride containing 3.5 g. of triethylamine. Dichloroacetyl chloride 4.4 g. was added dropwise with stirring to the reaction flask and cooled in a water bath at room temperature. When addition was complete, the mixture was stirred at room temperature for about 30 minutes, washed with water, separated and dried over anhydrous magnesium sulfate. The solvent was stripped off under vacuum. There was obtained a yield of 8.6 g. of the title compound, ND30 =1.5590.

후처리

  1. additionwas added dropwise
  2. additionWhen addition
  3. stirringthe mixture was stirred at room temperature for about 30 minutes
  4. washwashed with water
  5. customseparated
  6. dry with materialdried over anhydrous magnesium sulfate
  7. customThere was obtained a yield of 8.6 g

출처 및 근거

ORD 기록
ord-925a4eec6d354b5cbf7e5f77fde73a03
출처 데이터셋
uspto-grants-1984_11
특허 번호
US04483706

반응 노트

불러오는 중…