Acetone → HCID 12962350, 화합물

HRID 1979879노트

반응식

HRID 1979879 반응식
[C:1]1([CH:7]2[NH:11][CH2:10][CH2:9][S:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CC(C)=O.[Cl:16][CH:17]([Cl:21])[C:18](Cl)=[O:19]>O>[C:1]1([CH:7]2[N:11]([C:18](=[O:19])[CH:17]([Cl:21])[Cl:16])[CH2:10][CH2:9][S:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

5

반응물 3

HCID 180AcetoneHCID 6593Dichloroacetyl chlorideHCID 207062-Phenylthiazolidine

생성물 1

HCID 12962350HCID 12962350, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Five (5) grams of 2-phenyl thiazolidine was dissolved in 50 ml. of acetone, 3.1 g. of thiethylamine was added and the mixture stirred in a room temperature water bath, while 4.4 g. of dichloroacetyl chloride was added dropwise. The mixture was allowed to stand for about 30 minutes and then poured into water, extracted with methylene chloride, separated, dried over magnesium sulfate, and the solvent stripped under vacuum. There was obtained a yield of 7.3 g. of an oil, the title compound, ND30 =1.5836.

후처리

  1. additionof thiethylamine was added
  2. extractionextracted with methylene chloride
  3. customseparated
  4. dry with materialdried over magnesium sulfate
  5. customThere was obtained a yield of 7.3 g

출처 및 근거

ORD 기록
ord-9e04a2b60641407ca64955548d5ec253
출처 데이터셋
uspto-grants-1984_11
특허 번호
US04483706

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