Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-tert-Butylbenzenesulfonamide → N-[4-(hexadecylamino)benzoyl]-4-t-butylbenzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-tert-Butylbenzenesulfonamide | HCID 222872 | — |
| 반응물 | 4-Hexadecylaminobenzoyl chloride hydrochloride | HCID 13255322 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | N-[4-(hexadecylamino)benzoyl]-4-t-butylbenzenesulfonamide | HCID 20437349 | — |
반응 단계
A solution of 21.1 g. of 4-(hexadecylamino)benzoyl chloride hydrochloride and 10.8 g. of p-tert-butylbenzenesulfonamide in 250 ml. of pyridine was stirred under reflux for 2 hours and evaporated. The residue was partitioned between 1N hydrochloric acid and CH2Cl2 and the organic layer was separated, washed with water, dried (MgSO4), and evaporated. Crystallization of the residual glass from CH2Cl2 hexane afforded a white solid, melting point 173°-176° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04485105 |
| 출처 데이터셋 | uspto-grants-1984_11 |
| ORD ID | ord-6c61759175584884a699b25894682d7d |
| 출처 메모 | uspto-grants-1984_11 |