Ethylamine → 3-{2-[(5-Dimethylaminomethyl-2-thienyl)methylthio]ethylamino}-4-ethylamino-1,2,5-thiadiazole 1-oxide
반응식
CO[C:3]1[C:7](OC)=[N:6][S:5](=[O:10])[N:4]=1.[CH3:11][N:12]([CH2:14][C:15]1[S:19][C:18]([CH2:20][S:21][CH2:22][CH2:23][NH2:24])=[CH:17][CH:16]=1)[CH3:13].[CH2:25]([NH2:27])[CH3:26]>>[CH3:13][N:12]([CH2:14][C:15]1[S:19][C:18]([CH2:20][S:21][CH2:22][CH2:23][NH:24][C:3]2[C:7]([NH:27][CH2:25][CH3:26])=[N:6][S:5](=[O:10])[N:4]=2)=[CH:17][CH:16]=1)[CH3:11]참가 물질
4
실험 절차
When a solution of 3,4-dimethoxy-1,2,5-thiadiazole 1-oxide [prepared in Example 4, Step A] is successively reacted with an equimolar amount of 2-[(5-dimethylaminomethyl-2-thienyl)methylthio]ethylamine and excess ethylamine according to the procedure described in Example 18, the title compound is thereby produced.