Phenylhydrazine → 1-(3-Pyridinyl)ethanone 2-phenylhydrazone

HRID 1980878노트

반응식

HRID 1980878 반응식
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9]([C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1)(=O)[CH3:10].C(=O)(O)[O-].[Na+]>C(O)(=O)C>[C:1]1([NH:7][N:8]=[C:9]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)[CH3:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

5

반응물 3

HCID 7516PhenylhydrazineHCID 95893-AcetylpyridineHCID 516892Sodium Bicarbonate

생성물 1

HCID 36125761-(3-Pyridinyl)ethanone 2-phenylhydrazone

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A solution of 19.7 of phenylhydrazine (21.63 g) and 22 ml of 3-acetylpyridine (24.23 g) in glacial acetic acid (100 ml) is stirred and refluxed for 4.5 hours. The solution is cooled in an ice-water bath and neutralized with a saturated sodium bicarbonate solution (180 ml). The precipitate is collected, washed and dried to give 3-acetylpyridine phenylhydrazone.

후처리

  1. temperaturerefluxed for 4.5 hours
  2. temperatureThe solution is cooled in an ice-water bath
  3. customThe precipitate is collected
  4. washwashed
  5. customdried

출처 및 근거

ORD 기록
ord-9edef54adfa64d608e44529413a11723
출처 데이터셋
uspto-grants-1985_04
특허 번호
US04511573

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