Dichloromethane → 5-Chloromethyl-4-trifluoromethyl-2-(4-trifluoromethyl-phenyl)-pyrimidine

반응식

[Cl:27][CH2:28][Cl:29].[F:1][C:2]([c:3]1[n:4][c:5](-[c:11]2[cH:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]2)[n:6][cH:7][c:8]1[CH2:9][OH:10])([F:21])[F:22].[S:23]([Cl:24])([Cl:25])=[O:26]>>[F:1][C:2]([c:3]1[n:4][c:5](-[c:11]2[cH:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]2)[n:6][cH:7][c:8]1[CH2:9][Cl:25])([F:21])[F:22]

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 24386Thionyl Chloride

HCID 21935616[4-Trifluoromethyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-methanol

생성물 1

HCID 219357875-Chloromethyl-4-trifluoromethyl-2-(4-trifluoromethyl-phenyl)-pyrimidine

출처 및 근거

ORD 기록: ord-468b489417954a08a72e342b1fc510e7
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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