Ammonia → α-Phenyl-2-benzothiazolemethanamine

HRID 1981460노트

반응식

HRID 1981460 반응식
Cl.[NH2:2][CH:3]([C:10]1[S:11][C:12]2[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=2[N:14]=1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.N>C(Cl)Cl>[NH2:2][CH:3]([C:10]1[S:11][C:12]2[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=2[N:14]=1)[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

참가 물질

4

반응물 2

HCID 222AmmoniaHCID 23318519HCID 23318519, 화합물

생성물 1

HCID 13342005α-Phenyl-2-benzothiazolemethanamine

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

The hydrochloride was stirred with aqueous ammonia and methylene chloride, and the aqueous layer was extracted with two portions of methylene chloride. The combined methylene chloride extracts were washed with brine, dried over Na2SO4, filtered and concentrated in vacuo. 13.1 g of white solid, as desired product, was obtained, mp. 68°-70° C.

후처리

  1. extractionthe aqueous layer was extracted with two portions of methylene chloride
  2. washThe combined methylene chloride extracts were washed with brine
  3. dry with materialdried over Na2SO4
  4. filtrationfiltered
  5. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-5808603c1b1743d2b9708677bca3ab96
출처 데이터셋
uspto-grants-1986_06
특허 번호
US04592774

반응 노트

불러오는 중…