Pyrazole → Metazachlor

HRID 1981602

반응식

HRID 1981602 반응식
[Cl:1][CH2:2][C:3]([N:5]([CH2:14]Cl)[C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:13])=[O:4].[NH:16]1[CH:20]=[CH:19][CH:18]=[N:17]1>C1(C)C=CC=CC=1>[Cl:1][CH2:2][C:3]([N:5]([CH2:14][N:16]1[CH:20]=[CH:19][CH:18]=[N:17]1)[C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:13])=[O:4]

참가 물질

4

반응물 2

HCID 1048PyrazoleHCID 130698822-Chloro-N-(chloromethyl)-N-(2,6-dimethylphenyl)acetamide

생성물 1

HCID 49384Metazachlor

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

43.9 parts by weight of 2-chloro-2',6'-dimethyl-N-chloromethyl acetanilide and 25.8 parts by weight of pyrazole are stirred for 7 hours at 90° C. in 120 parts by volume of toluene. After the mixture has cooled it is filtered, and the filtrate is washed 3 times with water, each time with 50 parts by volume, and dried over sodium sulfate. The solvent is evaporated and the residue pasted with 50 parts by volume of petroleum ether to give 39.1 parts by weight of 2-chloro-2',6'-dimethyl-N-(pyrazol-1-yl-methyl)-acetanilide, m.p.: 81° C.

후처리

  1. temperatureAfter the mixture has cooled it
  2. filtrationis filtered
  3. washthe filtrate is washed 3 times with water
  4. dry with materialeach time with 50 parts by volume, and dried over sodium sulfate
  5. customThe solvent is evaporated

출처 및 근거

ORD 기록
ord-8adae3aea54c42aab829a92824e3ab1a
출처 데이터셋
uspto-grants-1986_06
특허 번호
US04593104

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