Ammonia → Ethyl 2-acetamido-3-aminobut-2-enoate
반응식
[NH3:1].[C:2]([NH:5][CH:6]([C:12]([CH3:14])=O)[C:7]([O:9][CH2:10][CH3:11])=[O:8])(=[O:4])[CH3:3]>C(O)C>[C:2]([NH:5][C:6](=[C:12]([NH2:1])[CH3:14])[C:7]([O:9][CH2:10][CH3:11])=[O:8])(=[O:4])[CH3:3]참가 물질
4
반응 조건
- 온도
- 23 °C
실험 절차
A solution of 0.054 mmol of ammonia in ethanol was added dropwise to 0.054 mol of ethyl 2-acetamidoacetoacetate in 40 ml of ice cold ethanol over a period of 10 minutes. The reaction vessel was tightly capped and allowed to stir overnight at 23° C., after which the solvent was removed at reduced pressure to provide ethyl 2-acetamido-3-aminobut-2-enoate in a 3/1 ratio of two geometrical isomers.
후처리
- customThe reaction vessel was tightly capped
- customafter which the solvent was removed at reduced pressure
출처 및 근거
- ORD 기록
- ord-80c66047b6b5402985af6d7c529af9bf
- 출처 데이터셋
- uspto-grants-1986_06
- 특허 번호
- US04593118
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