Imidazole → N-(3,5-bis-Trifluoromethyl-benzyl)-6-(4-formyl-piperazin-1-yl)-N-methyl-4-o-tolyl-nicotinamide

반응식

[CH3:1][N:2]([CH:3]=[O:4])[CH3:5].[F:11][C:12]([c:13]1[cH:14][c:15]([CH2:16][N:17]([C:18]([c:19]2[cH:20][n:21][c:22]([N:32]3[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]3)[cH:23][c:24]2-[c:25]2[c:26]([CH3:31])[cH:27][cH:28][cH:29][cH:30]2)=[O:38])[CH3:39])[cH:40][c:41]([C:43]([F:44])([F:45])[F:46])[cH:42]1)([F:47])[F:48].[nH:6]1[cH:7][cH:8][n:9][cH:10]1>>[CH:3](=[O:4])[N:35]1[CH2:34][CH2:33][N:32]([c:22]2[n:21][cH:20][c:19]([C:18]([N:17]([CH2:16][c:15]3[cH:14][c:13]([C:12]([F:11])([F:47])[F:48])[cH:42][c:41]([C:43]([F:44])([F:45])[F:46])[cH:40]3)[CH3:39])=[O:38])[c:24](-[c:25]3[c:26]([CH3:31])[cH:27][cH:28][cH:29][cH:30]3)[cH:23]2)[CH2:37][CH2:36]1