Sulfuric Acid → N(m-propionamidophenyl)-2,2-dimethylsuccinimide

HRID 1982078노트

반응식

HRID 1982078 반응식
S(=O)(=O)(O)O.[NH2:6][C:7]1[CH:8]=[C:9]([N:13]2[C:17](=[O:18])[CH2:16][C:15]([CH3:20])([CH3:19])[C:14]2=[O:21])[CH:10]=[CH:11][CH:12]=1>C(OC(=O)CC)(=O)CC.O>[C:17]([NH:6][C:7]1[CH:8]=[C:9]([N:13]2[C:17](=[O:18])[CH2:16][C:15]([CH3:19])([CH3:20])[C:14]2=[O:21])[CH:10]=[CH:11][CH:12]=1)(=[O:18])[CH2:16][CH3:15]

참가 물질

5

반응물 2

HCID 1118Sulfuric AcidHCID 13189216N-m-AMINOPHENYL-2,2-DIMETHYLSUCCINIMIDE

생성물 1

HCID 23317140N(m-propionamidophenyl)-2,2-dimethylsuccinimide

시약·촉매·용매 2

HCID 31263Propionic anhydride촉매HCID 962Water용매

실험 절차

Five and one half g. of propionic anhydride containing one drop of concentrated sulfuric acid was mixed at ambient temperature with 8.7 g. of N-m-aminophenyl-2,2-dimethylsuccinimide in a small beaker. The mixture became very hot and on cooling was poured into water and extracted with methylene chloride, which was dried and stripped under vacuum yielding 9.5 g. of a glassy product. The product was identified as the title compound by analysis of infrared spectra.

후처리

  1. temperatureon cooling
  2. extractionextracted with methylene chloride, which
  3. customwas dried
  4. customyielding 9.5 g

출처 및 근거

ORD 기록
ord-2cf23612caed45fb91d44532bc23b0cb
출처 데이터셋
uspto-grants-1986_06
특허 번호
US04595408

반응 노트

불러오는 중…