HCID 13645890, 화합물 → HCID 14203029, 화합물

HRID 1982263노트

반응식

HRID 1982263 반응식
[O:1]1[CH2:21][CH:2]1[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([Cl:12])[C:6]=1[O:13]CC1C=CC=CC=1>C(OCC)(=O)C.[Pd]>[O:1]1[CH2:21][CH:2]1[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([Cl:12])[C:6]=1[OH:13]

참가 물질

4

반응물 1

HCID 13645890HCID 13645890, 화합물

생성물 1

HCID 14203029HCID 14203029, 화합물수율 106.3%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8857Ethyl Acetate용매

실험 절차

In 140 ml of ethyl acetate, 5.595 g of 1-(2,3-epoxypropyloxy)-2-benzyloxy-3,4-dichlorobenzene is hydrogenated under atmospheric pressure using 1.65 g of 5% palladium on carbon (50% moisture) as catalyst (for 20 minutes, 625 ml of hydrogen gas is absorbed.). After the catalyst is filtered off, the filtrate is evaporated to give 4.3 g of 1-(2,3-epoxypropyloxy)-2-hydroxy-3,4-dichlorobenzene.

후처리

  1. custom(for 20 minutes, 625 ml of hydrogen gas is absorbed.)
  2. filtrationAfter the catalyst is filtered off
  3. customthe filtrate is evaporated

출처 및 근거

ORD 기록
ord-d4bc558cffe04c2cbdfda504c172827b
출처 데이터셋
uspto-grants-1986_06
특허 번호
US04595767

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