Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 1,2-Dibenzyloxy-2-hydroxy-3,4-dichlorobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | 3,4-Dichlorocatechol | HCID 19877 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 1,2-Dibenzyloxy-2-hydroxy-3,4-dichlorobenzene | HCID 23317733 | — |
반응 단계
In 250 ml of dimethylformamide is dissolved 8.95 g of the compound (II), and 4.80 g (2 equivalent) of 50% sodium hydride oily suspension and 10.25 g (1.3 equivalent) of benzyl bromide are added thereto. The mixture is stirred for 10 minutes under ice cooling, then poured into 200 ml of water, and sparingly soluble crystals are collected by filtration and recrystallized from hexane to give 2.096 g of 1,2-dibenzyloxy-2-hydroxy-3,4-dichlorobenzene, mp. 74°-75° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04595767 |
| 출처 데이터셋 | uspto-grants-1986_06 |
| ORD ID | ord-8e725f34052144fb81d94d40b125487e |
| 출처 메모 | uspto-grants-1986_06 |