3-(Dimethylamino)benzoic acid → HCID 13651729, 화합물

반응식

[CH2:1]([N:3]([CH2:12][C:13]1C=CC=CC=1)[C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[O:9])=[CH:6][CH:5]=1)[CH3:2].[CH3:19][N:20]([CH3:30])[C:21]1[CH:22]=[C:23]([CH:27]=[CH:28][CH:29]=1)[C:24](O)=[O:25]>>[CH2:12]([N:3]([CH2:1][CH3:2])[C:4]1[CH:5]=[CH:6][C:7]([CH:8]2[C:27]3[C:23](=[CH:22][C:21]([N:20]([CH3:30])[CH3:19])=[CH:29][CH:28]=3)[C:24](=[O:25])[O:9]2)=[CH:10][CH:11]=1)[CH3:13]

참가 물질

반응물 2

HCID 668373-(Dimethylamino)benzoic acid

HCID 2822694-[Ethyl(phenylmethyl)amino]benzaldehyde

생성물 1

HCID 13651729HCID 13651729, 화합물

실험 절차

Employing a procedure similar to that described in Example 1, part A above, for interacting 7.2 g of 4-(N-ethylbenzylamino)benzaldehyde and 5.2 g of 3-dimethylaminobenzoic acid, there was obtained 7.5 g of 3-4-(N-ethylbenzylamino)phenyl]-6-dimethylaminophthalide (Formula II: R=CH3 ; X=H; Y=(C6H5CH2)(C2H5)NC6H4) as a viscous oil.

출처 및 근거

ORD 기록: ord-086714df0cfe44b39c79667ea2a6961c
출처 데이터셋: uspto-grants-1986_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04595768

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