Allyl bromide → 4-Hydroxy-1-phenyl-3-(prop-2-en-1-yl)-1,8-naphthyridin-2(1H)-one

반응식

BrCCC=C.C(Br)C=C.[CH2:10]([C:14]1[C:15](=[O:31])[N:16]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:17]2[C:22]([C:23]=1[OH:24])=[CH:21][CH:20]=[CH:19][N:18]=2)[CH2:11][CH:12]=C>>[OH:24][C:23]1[C:22]2[C:17](=[N:18][CH:19]=[CH:20][CH:21]=2)[N:16]([C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)[C:15](=[O:31])[C:14]=1[CH2:10][CH:11]=[CH2:12]

참가 물질

반응물 3

HCID 7841Allyl bromide

HCID 21241Homoallyl bromide

HCID 54737812HCID 54737812, 화합물

생성물 1

HCID 546860954-Hydroxy-1-phenyl-3-(prop-2-en-1-yl)-1,8-naphthyridin-2(1H)-one

실험 절차

In a similar manner, substitute 4-bromo-1-butene for allyl bromide in part B(1) of Preparation 1 to prepare 3-(3-butenyl)-4-hydroxy-1-phenyl-1,8-naphthyridin-2(1H)-one.

출처 및 근거

ORD 기록: ord-fcdbbf861f014eecb2f84dc4981cd568
출처 데이터셋: uspto-grants-1986_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04596809

반응 노트

불러오는 중…