Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Imidazole → 8-Phenyl-5,6-dihydroimidazo[1,2-a]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Imidazole | HCID 795 | — |
| 반응물 | Cyclopropyl phenyl ketone | HCID 77029 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 8-Phenyl-5,6-dihydroimidazo[1,2-a]pyridine | HCID 13764012 | — |
반응 단계
Combine 25 g (0.17 mol) of cyclopropyl phenyl ketone with 50 g (0.73 mol) of imidazole, and heat to 200° C. for 18 hr. Isolation from 200 g of silica gel using methylene chloride, followed by crystallization from ether provides the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04596872 |
| 출처 데이터셋 | uspto-grants-1986_06 |
| ORD ID | ord-4545ff0b998542439203efaef455be6b |
| 출처 메모 | uspto-grants-1986_06 |