Thionyl Chloride → 3-i-propyl-1-(chloromethyl)-1H-pyrazole hydrochloride

HRID 1982994노트

반응식

HRID 1982994 반응식
[CH:1]([C:4]1[CH:8]=[CH:7][N:6]([CH2:9]O)[N:5]=1)([CH3:3])[CH3:2].S(Cl)([Cl:13])=O>ClCCl>[ClH:13].[CH:1]([C:4]1[CH:8]=[CH:7][N:6]([CH2:9][Cl:13])[N:5]=1)([CH3:3])[CH3:2]

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 23149190[3-(propan-2-yl)-1H-pyrazol-1-yl]methanol

생성물 1

HCID 231491783-i-propyl-1-(chloromethyl)-1H-pyrazole hydrochloride

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

1.28 g of 3-i-propyl-1H-pyrazole-1-ylmethanol was dissolved to 20 ml of dichloromethane. 2 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 1.58 g of 3-i-propyl-1-(chloromethyl)-1H-pyrazole hydrochloride.

후처리

  1. concentrationThe reaction mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-c6f5aa9115c248108b26d7c6ed139dad
출처 데이터셋
uspto-grants-2009_06
특허 번호
US07541374B2

반응 노트

불러오는 중…