Thionyl Chloride → 1-(chloromethyl)-3,5-dimethyl-1H-pyrazole hydrochloride
반응식
[CH3:1][C:2]1[CH:6]=[C:5]([CH3:7])[N:4]([CH2:8]O)[N:3]=1.S(Cl)([Cl:12])=O>ClCCl>[ClH:12].[Cl:12][CH2:8][N:4]1[C:5]([CH3:7])=[CH:6][C:2]([CH3:1])=[N:3]1참가 물질
4
실험 절차
0.63 g of 3,5-dimethyl-1H-pyrazole-1-ylmethanol was dissolved to 25 ml of dichloromethane. 1.2 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 0.93 g of 1-(chloromethyl)-3,5-dimethyl-1H-pyrazole hydrochloride.
후처리
- concentrationThe reaction mixture was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-571f806eb95f40789a06bdbe4b8b9f32
- 출처 데이터셋
- uspto-grants-2009_06
- 특허 번호
- US07541374B2
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