Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(tert-butoxycarbonyl)-2-aminoethanethiol → (2-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-5-ylsulfanyl}-ethyl)-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(tert-butoxycarbonyl)-2-aminoethanethiol | HCID 3017761 | — |
| 반응물 | 1-(5-Bromothiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-urea | HCID 59732797 | — |
| 생성물 | (2-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-5-ylsulfanyl}-ethyl)-carbamic acid tert-butyl ester | HCID 59732686 | 40% |
반응 단계
(2-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-5-ylsulfanyl}-ethyl)-carbamic acid tert-butyl ester (202 mg, 40%) was prepared from 1-(5-bromo-thiazol-2-yl)-3-(2-cyclo pentanecarbonyl-4-methyl-phenyl)-urea (408 mg, 1 mmol) and (2-mercapto-ethyl)-carbamic acid tert-butyl ester (354 mg, 2 mmol) following the general procedure Q.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07541373B2 |
| 출처 데이터셋 | uspto-grants-2009_06 |
| ORD ID | ord-370f8ab1596a4464b70cc64219abfd49 |
| 출처 메모 | uspto-grants-2009_06 |