Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Aminothiazole → 1-[2-(2-Methoxy-benzoyl)-4-methyl-phenyl]-3-thiazol-2-yl-urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Aminothiazole | HCID 2155 | — |
| 반응물 | 2-Amino-5-methylbenzoic acid | HCID 76255 | — |
| 반응물 | (2-Amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone | HCID 66998824 | — |
| 생성물 | 1-[2-(2-Methoxy-benzoyl)-4-methyl-phenyl]-3-thiazol-2-yl-urea | HCID 59733095 | 72% |
| 생성물 | (2-Amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone | HCID 66998824 | 35% |
반응 단계
(2-Amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone (843 g, 35%) was prepared from 2-amino-5-methyl-benzoic acid (1.51 g, 0.1 mol) following the general procedure S. 1-[2-(2-methoxy-benzoyl)-4-methyl-phenyl]-3-thiazol-2-yl-urea (132 mg, 72%) was prepared from (2-amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone (121 mg, 0.5 mmol) and 2-aminothiazole (0.060 g, 0.6 mmol) following the general procedure D.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07541373B2 |
| 출처 데이터셋 | uspto-grants-2009_06 |
| ORD ID | ord-f35c48e1bbff4892981b778347ede290 |
| 출처 메모 | uspto-grants-2009_06 |