Ethyl isocyanate → N-ethyl-4-(pent-4-ynyl)piperazine-1-carboxamide

HRID 1984093노트

반응식

HRID 1984093 반응식
[CH2:1]([N:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)[CH2:2][CH2:3][C:4]#[CH:5].[CH2:12]([N:14]=[C:15]=[O:16])[CH3:13]>C(Cl)Cl>[CH2:12]([NH:14][C:15]([N:9]1[CH2:8][CH2:7][N:6]([CH2:1][CH2:2][CH2:3][C:4]#[CH:5])[CH2:11][CH2:10]1)=[O:16])[CH3:13]

참가 물질

4

반응물 2

HCID 8022Ethyl isocyanateHCID 866082211-(Pent-4-yn-1-yl)piperazine

생성물 1

HCID 86608224N-ethyl-4-(pent-4-ynyl)piperazine-1-carboxamide

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A solution of 1-(pent-4-ynyl)piperazine (1.08) in DCM (5 mL) was treated with ethyl isocyanate (0.56 mL) at rt for 2 h, and evaporated to yield N-ethyl-4-(pent-4-ynyl)piperazine-1-carboxamide.

후처리

  1. customevaporated

출처 및 근거

ORD 기록
ord-b909f49fa01449bf8781c00e62d9f529
출처 데이터셋
uspto-grants-2009_06
특허 번호
US07544672B2

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