Imidazole → HCID 19854577, 화합물
반응식
CC1C=CC(S(O[CH2:12][CH2:13][C:14]#[CH:15])(=O)=O)=CC=1.[NH:16]1[CH:20]=[CH:19][N:18]=[CH:17]1.C([O-])([O-])=O.[K+].[K+].C(Cl)Cl>CC(=O)CC.O>[CH2:12]([N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1)[CH2:13][C:14]#[CH:15]참가 물질
7
실험 절차
A mixure of but-3-ynyl 4-methylbenzenesulfonate (1.04 g), imidazole (573 mg) and K2CO3 (3.88 g) in 2-butanone (10 mL) was heated to reflux overnight. Work-up (DCM, H2O), drying (Na2SO4) and concentration gave 1-(but-3-ynyl)-1H-imidazole (501 mg).
후처리
- temperatureto reflux overnight
- customdrying
- concentration(Na2SO4) and concentration
출처 및 근거
- ORD 기록
- ord-d98c0b1ef83c4f88b903e1fe780e1065
- 출처 데이터셋
- uspto-grants-2009_06
- 특허 번호
- US07544672B2
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