Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-amino-N-cyclopropyl-2,4-difluorobenzamide → N-Cyclopropyl-2,4-difluoro-5-{[2-(4-methyl-pyridin-2-ylamino)-thiazol-5-ylmethyl]-amino}-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-amino-N-cyclopropyl-2,4-difluorobenzamide | HCID 21966507 | — |
| 반응물 | 2-(4-Methylpyridin-2-ylamino)-thiazole-5-carbaldehyde | HCID 22019084 | — |
| 생성물 | N-Cyclopropyl-2,4-difluoro-5-{[2-(4-methyl-pyridin-2-ylamino)-thiazol-5-ylmethyl]-amino}-benzamide | HCID 22019101 | — |
반응 단계
2-(4-Methylpyridin-2-ylamino)-thiazole-5-carbaldehyde was treated with 5-amino-N-cyclopropyl-2,4-difluorobenzamide (for preparation see Example 18) in a manner similar to Example 1 to afford the title compound. LC/MS; (M+H)+=416.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07547711B2 |
| 출처 데이터셋 | uspto-grants-2009_06 |
| ORD ID | ord-9f447ec6b9c74655b72d78bf23fb0aef |
| 출처 메모 | uspto-grants-2009_06 |