Methanol → HCID 66894422, 화합물

반응식

[NH2:1][C@@H:2]([CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[Cl:13])[C:3]([OH:5])=[O:4].[CH3:14]O>>[ClH:13].[CH3:14][O:4][C:3](=[O:5])[C@@H:2]([NH2:1])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[Cl:13]

참가 물질

반응물 2

HCID 887Methanol

HCID 27614912-Chloro-L-phenylalanine

생성물 1

HCID 66894422HCID 66894422, 화합물

실험 절차

2(S)-Amino-3-(2-chlorophenyl)propionic acid (1 g, commercially available) was dissolved in methanol (10 mL) and HCl gas was bubbled through the solution for 5 min. The reaction mixture was stirred at room temperature for 3 h and the solvent was evaporated using the rotavap to get 2(S)-amino-3-(2-chlorophenyl)propionic acid methyl ester hydrochloride (1.2 g).

후처리

customHCl gas was bubbled through the solution for 5 min
customthe solvent was evaporated

출처 및 근거

ORD 기록: ord-b21c25fc386f40ea977dd0f731e0f883
출처 데이터셋: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07547701B2

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