참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-(4-Methoxyphenyl)malondialdehyde | HCID 3849370 | — |
| 반응물 | 4-iodo-1H-pyrazol-3-amine | HCID 12831626 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-Iodo-6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine | HCID 57722613 | — |
반응 단계
A solution of 4-iodo-1H-pyrazol-5-amine (640 mg, 3.9 mmol, 1 equiv) and 2-(4-methoxyphenyl)malonaldehyde (700 mg, 3.9 mmol, 1.0 equiv) in ethanol (20 mL) was heated at 75° C. for 4 hours. The reaction mixture was allowed to cool to 23° C., and the precipitate was filtered, washed with cold methanol, and air dried to afford 3-iodo-6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine (2-1) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07550470B2 |
|---|
| 출처 데이터셋 | uspto-grants-2009_06 |
|---|
| ORD ID | ord-1044e8cbed614475a0afc876cf2e1da6 |
|---|
| 출처 메모 | uspto-grants-2009_06 |
|---|
