Cyclopropanemethanamine → N-Cyclopropyl-3-(1-{2-[(cyclopropylmethyl)amino]-2-oxoethyl}-1H-indazol-5-yl)-4-methylbenzamide
반응식
[CH:1]1([NH:4][C:5]([C:7]2[CH:8]=[CH:9][C:10]([CH3:27])=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23](OC)=[O:24])[N:17]=[CH:16]4)[CH:12]=2)=[O:6])[CH2:3][CH2:2]1.[CH:28]1([CH2:31][NH2:32])[CH2:30][CH2:29]1>>[CH:1]1([NH:4][C:5](=[O:6])[C:7]2[CH:8]=[CH:9][C:10]([CH3:27])=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23]([NH:32][CH2:31][CH:28]3[CH2:30][CH2:29]3)=[O:24])[N:17]=[CH:16]4)[CH:12]=2)[CH2:3][CH2:2]1참가 물질
3
실험 절차
Example 129 was prepared by General Method D using methyl (5-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-1H-indazol-1-yl)acetate (Example 117) and 1-cyclopropylmethanamine to give the title compound (0.015 g).
후처리
- customExample 129 was prepared by General Method D
출처 및 근거
- ORD 기록
- ord-8365baaba80c487fbdc75be610d83df3
- 출처 데이터셋
- uspto-grants-2010_01