4-(aminomethyl)-N-methylbenzamide → HCID 58656478, 화합물

HRID 1988951노트

반응식

HRID 1988951 반응식
[CH:1]1([NH:4][C:5]([C:7]2[CH:8]=[C:9]([F:28])[C:10]([CH3:27])=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23](OC)=[O:24])[N:17]=[CH:16]4)[CH:12]=2)=[O:6])[CH2:3][CH2:2]1.[NH2:29][CH2:30][C:31]1[CH:40]=[CH:39][C:34]([C:35]([NH:37][CH3:38])=[O:36])=[CH:33][CH:32]=1>>[CH:1]1([NH:4][C:5](=[O:6])[C:7]2[CH:12]=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23]([NH:29][CH2:30][C:31]3[CH:32]=[CH:33][C:34]([C:35]([NH:37][CH3:38])=[O:36])=[CH:39][CH:40]=3)=[O:24])[N:17]=[CH:16]4)[C:10]([CH3:27])=[C:9]([F:28])[CH:8]=2)[CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 167770714-(aminomethyl)-N-methylbenzamideHCID 58656520HCID 58656520, 화합물

생성물 1

HCID 58656478HCID 58656478, 화합물

실험 절차

Example 135 was prepared by General Method D using methyl (5-{5-[(cyclopropylamino)carbonyl]-3-fluoro-2-methylphenyl}-H-indazol-1-yl)acetate (Example 123) and 4-(aminomethyl)-N-methylbenzamide to give the title compound (0.005 g).

후처리

  1. customExample 135 was prepared by General Method D

출처 및 근거

ORD 기록
ord-6a02a93017c741ec908d455b144cc27f
출처 데이터셋
uspto-grants-2010_01
특허 번호
US07642276B2

반응 노트

불러오는 중…