4-(3,4-Diamino-phenoxy)-pyridine-2-carboxylic acid methylamide → HCID 178485498, 화합물

HRID 1988971

반응식

HRID 1988971 반응식
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][N:6]=[C:5]2[CH:11]=O.[CH3:13][NH:14][C:15]([C:17]1[CH:22]=[C:21]([O:23][C:24]2[CH:29]=[CH:28][C:27]([NH2:30])=[C:26]([NH2:31])[CH:25]=2)[CH:20]=[CH:19][N:18]=1)=[O:16]>>[CH3:13][NH:14][C:15]([C:17]1[CH:22]=[C:21]([O:23][C:24]2[CH:29]=[CH:28][C:27]3[NH:30][C:11]([C:5]4[C:4]5[C:8](=[CH:9][CH:10]=[C:2]([F:1])[CH:3]=5)[NH:7][N:6]=4)=[N:31][C:26]=3[CH:25]=2)[CH:20]=[CH:19][N:18]=1)=[O:16]

참가 물질

3

반응물 2

HCID 177564924-(3,4-Diamino-phenoxy)-pyridine-2-carboxylic acid methylamideHCID 178520032HCID 178520032, 화합물

생성물 1

HCID 178485498HCID 178485498, 화합물

실험 절차

The title compound was synthesized from 5-fluoro-1H-indazole-3-carbaldehyde and 4-(3,4-diamino-phenoxy)-pyridine-2-carboxylic acid methylamide using the method described above in Example 4. LC/MS (m/z) 403.1 (MH+), Rt 2.26 minutes.

출처 및 근거

ORD 기록
ord-7bd1588b84d441408f719854587d7406
출처 데이터셋
uspto-grants-2010_01
특허 번호
US07642278B2

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