(3-Bromophenyl)boronic acid → 2-(3-Bromo-phenyl)-4-(4-chloro-phenyl)-6-methylpyridine

HRID 1989169노트

반응식

HRID 1989169 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[C:12]([CH3:14])[N:11]=[C:10](I)[CH:9]=2)=[CH:4][CH:3]=1.[Br:16][C:17]1[CH:18]=[C:19](B(O)O)[CH:20]=[CH:21][CH:22]=1>>[Br:16][C:17]1[CH:18]=[C:19]([C:10]2[CH:9]=[C:8]([C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=3)[CH:13]=[C:12]([CH3:14])[N:11]=2)[CH:20]=[CH:21][CH:22]=1

참가 물질

3

반응물 2

HCID 2734318(3-Bromophenyl)boronic acidHCID 574686424-(4-Chloro-phenyl)-2-iodo-6-methyl-pyridine

생성물 1

HCID 574687502-(3-Bromo-phenyl)-4-(4-chloro-phenyl)-6-methylpyridine

실험 절차

The title compound was prepared from 4-(4-chloro-phenyl)-2-iodo-6-methyl-pyridine (example A.29) (1.5 g, 5 mmol) and commercially available 3-bromo-benzene-boronic acid

출처 및 근거

ORD 기록
ord-318363dabafb4924a172e6fd4544d0ff
출처 데이터셋
uspto-grants-2010_01
특허 번호
US07642264B2

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