HCID 57468665, 화합물 → HCID 57468786, 화합물

HRID 1989204노트

반응식

HRID 1989204 반응식
Cl[C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([Cl:14])[CH:9]=2)[CH:5]=[C:4]([C:15]([F:18])([F:17])[F:16])[N:3]=1.[I:19][C:20]1[N:21]=[CH:22][NH:23][CH:24]=1>>[Cl:14][C:10]1[CH:9]=[C:8]([C:6]2[CH:5]=[C:4]([C:15]([F:18])([F:17])[F:16])[N:3]=[C:2]([N:23]3[CH:24]=[C:20]([I:19])[N:21]=[CH:22]3)[N:7]=2)[CH:13]=[CH:12][CH:11]=1

참가 물질

3

반응물 2

HCID 57468665HCID 57468665, 화합물HCID 178506559HCID 178506559, 화합물

생성물 1

HCID 57468786HCID 57468786, 화합물

실험 절차

The title compound was prepared from 2-chloro-4-(3-chloro-phenyl)-6-trifluoromethyl-pyrimidine (example A.44) (3.12 g, 10.6 mmol) and commercially available 4-iodo-imidazole (2.27 g, 11.7 mmol) according to the general procedure IVa. Obtained as an off-white solid (4.0 g, 83%). MS (ISP) 451.0 [(M+H)+]; mp 202° C.

출처 및 근거

ORD 기록
ord-c35eeba128a448a598d4d755fa1c2d7c
출처 데이터셋
uspto-grants-2010_01
특허 번호
US07642264B2

반응 노트

불러오는 중…