2,3-Dichloronitrobenzene → (7-Chloro-1H-benzimidazol-1-yl)acetic acid

HRID 1991186노트

반응식

HRID 1991186 반응식
Br[C:2]1[C:7]2[N:8]([CH2:11][C:12]([OH:14])=[O:13])[CH:9]=[N:10][C:6]=2[CH:5]=[CH:4][CH:3]=1.[Cl:15]C1C=CC=C([N+]([O-])=O)C=1Cl>>[Cl:15][C:2]1[C:7]2[N:8]([CH2:11][C:12]([OH:14])=[O:13])[CH:9]=[N:10][C:6]=2[CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 185552,3-DichloronitrobenzeneHCID 11470826(7-bromo-1H-benzimidazol-1-yl)acetic acid

생성물 1

HCID 11206606(7-Chloro-1H-benzimidazol-1-yl)acetic acid

실험 절차

Alternatively, the title compound was synthesised according to the procedure described for the synthesis of (7-bromo-1H-benzimidazol-1-yl)acetic acid (parts A-D) starting from 1,2-dichloro-3-nitrobenzene. The new intermediates isolated were:

후처리

  1. customThe new intermediates isolated

출처 및 근거

ORD 기록
ord-432688e682954a388ee3920837737f30
출처 데이터셋
uspto-grants-2010_01
특허 번호
US07645784B2

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