Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclopropylamine → 2-Chloro-4-fluoro-5-[(cyclopropylamino)sulfonyl]benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclopropylamine | HCID 69828 | — |
| 반응물 | 3-(Chlorosulfonyl)-4-fluorobenzoic acid | HCID 3929891 | — |
| 반응물 | 2-Chloro-5-[(ethylamino)sulfonyl]-4-fluorobenzoic acid | HCID 58728052 | — |
| 생성물 | 2-Chloro-4-fluoro-5-[(cyclopropylamino)sulfonyl]benzoic acid | HCID 58728329 | — |
반응 단계
1.005 g (3.6 mmol) 3-chlorosulfonyl-4-fluorobenzoic acid was added to 0.76 mL (10.9 mmol) cyclopropylamine following the general procedure in for 2-chloro-5-[(ethylamino)sulfonyl]-4-fluorobenzoic acid. Crude product was used in subsequent step without further purification
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07645771B2 |
| 출처 데이터셋 | uspto-grants-2010_01 |
| ORD ID | ord-a951a2a29afa4151a97c8004fedd0b81 |
| 출처 메모 | uspto-grants-2010_01 |