Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Chlorophenyl)boronic acid → (4-Benzenesulfonyl-piperazin-1-yl)-[1-(3-chloro-phenyl)-5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Chlorophenyl)boronic acid | HCID 2734323 | — |
| 반응물 | (4-Benzenesulfonyl-piperazin-1-yl)-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone | HCID 68535846 | — |
| 생성물 | (4-Benzenesulfonyl-piperazin-1-yl)-[1-(3-chloro-phenyl)-5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone | HCID 24986571 | 47% |
반응 단계
The title compound was synthesized in analogy to example 5, from (4-benzenesulfonyl-piperazin-1-yl)-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone (example 13) and 3-chlorophenylboronic acid to afford the desired product as a light brown foam (47%). MS (ISP): 634.3 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07648979B2 |
| 출처 데이터셋 | uspto-grants-2010_01 |
| ORD ID | ord-77a8acdb58bc4a6494adf821ff9b7fa7 |
| 출처 메모 | uspto-grants-2010_01 |