Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloropyridine-5-boronic acid → HCID 86621934, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloropyridine-5-boronic acid | HCID 3845034 | — |
| 반응물 | 1-{4-[5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indole-2-carbonyl]-piperazin-1-yl}-2-methyl-propan-1-one | HCID 68533986 | — |
| 생성물 | HCID 86621934 | HCID 86621934 | 43% |
반응 단계
The title compound was synthesized in analogy to example 5, after stirring for 6.5 days at 35° C., from 1-{4-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carbonyl]-piperazin-1-yl}-2-methyl-propan-1-one (example 31) and 2-chloropyridine-5-boronic acid to afford the desired product as a light-brown foam (43%). MS (ISP): 565.4 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07648979B2 |
| 출처 데이터셋 | uspto-grants-2010_01 |
| ORD ID | ord-48068902e7554ae2a713a7b848d839c9 |
| 출처 메모 | uspto-grants-2010_01 |