Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
n,n-Dimethylpiperazine-1-carboxamide → 4-[2-(4-Dimethylcarbamoyl-piperazine-1-carbonyl)-1H-indole-5-carbonyl]-[1,4]diazepane-1-carboxylic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | n,n-Dimethylpiperazine-1-carboxamide | HCID 712909 | — |
| 반응물 | 5-(4-tert-butoxycarbonyl-[1,4]diazepane-1-carbonyl)-1H-indole-2-carboxylic acid | HCID 68535629 | — |
| 생성물 | 4-[2-(4-Dimethylcarbamoyl-piperazine-1-carbonyl)-1H-indole-5-carbonyl]-[1,4]diazepane-1-carboxylic acid tert-butyl ester | HCID 68535601 | — |
반응 단계
The title compound was synthesized in analogy to example 47a), from 5-(4-tert-butoxycarbonyl-[1,4]diazepane-1-carbonyl)-1H-indole-2-carboxylic acid and piperazine-1-carboxylic acid dimethyl amide. White solid. MS (m/z): 527.3 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07648979B2 |
| 출처 데이터셋 | uspto-grants-2010_01 |
| ORD ID | ord-8b93f7b9ac634218bbfabff3beea3934 |
| 출처 메모 | uspto-grants-2010_01 |