1-(2,4-Difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid → 1-(2,4-Difluorophenyl)-6,8-difluoro-1,4-dihydro-7-[2-(2-methylaminoethyl)morpholino]-4-oxoquinoline-3-carboxylic acid

반응식

[CH3:26][NH:27][CH2:28][CH2:29][CH:30]1[O:31][CH2:32][CH2:33][NH:34][CH2:35]1.[F:1][c:2]1[c:3](-[n:9]2[cH:10][c:11]([C:23](=[O:24])[OH:25])[c:12](=[O:22])[c:13]3[cH:14][c:15]([F:21])[c:16]([F:20])[c:17]([F:19])[c:18]23)[cH:4][cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[c:3](-[n:9]2[cH:10][c:11]([C:23](=[O:24])[OH:25])[c:12](=[O:22])[c:13]3[cH:14][c:15]([F:21])[c:16]([N:34]4[CH2:33][CH2:32][O:31][CH:30]([CH2:29][CH2:28][NH:27][CH3:26])[CH2:35]4)[c:17]([F:19])[c:18]23)[cH:4][cH:5][c:6]([F:8])[cH:7]1

참가 물질

반응물 2

HCID 144760111-(2,4-Difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

HCID 14652595HCID 14652595, 화합물

생성물 1

HCID 198349561-(2,4-Difluorophenyl)-6,8-difluoro-1,4-dihydro-7-[2-(2-methylaminoethyl)morpholino]-4-oxoquinoline-3-carboxylic acid

출처 및 근거

ORD 기록: ord-442b6ec85bc240e7a3ec2cbe81386eb0
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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