5-Bromo-2-hydroxy-3-methoxybenzaldehyde → 6-[4-(5-Bromo-2-hydroxy-3-methoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

HRID 1993411

반응식

HRID 1993411 반응식
[N:1]1([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[Br:14][C:15]1[CH:16]=[C:17]([O:24][CH3:25])[C:18]([OH:23])=[C:19]([CH:22]=1)[CH:20]=O>>[Br:14][C:15]1[CH:16]=[C:17]([O:24][CH3:25])[C:18]([OH:23])=[C:19]([CH:22]=1)[CH2:20][N:4]1[CH2:5][CH2:6][N:1]([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:2][CH2:3]1

참가 물질

3

반응물 2

HCID 2622385-Bromo-2-hydroxy-3-methoxybenzaldehydeHCID 1361025406-piperazin-1-yl-3H-pyrimidin-4-one2회

생성물 1

HCID 1361025766-[4-(5-Bromo-2-hydroxy-3-methoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

실험 절차

6-[4-(5-Bromo-2-hydroxy-3-methoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure A from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 5-bromo-2-hydroxy-3-methoxybenzaldehyde. Mass spectrum (ES) MH+=395.

출처 및 근거

ORD 기록
ord-68c3bb565e94463fba366af0e09e4ea3
출처 데이터셋
uspto-grants-2010_01
특허 번호
US07652013B2

연결된 노트

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