HCID 58659424, 화합물 → 1-[4-(6-Amino-pyrimidin-4-ylmethyl)-phenyl]-3-p-tolyl-urea
반응식
[NH2:1][C:2]1[N:7]=[CH:6][N:5]=[C:4]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([NH:15][C:16]([NH:18][C:19]3[CH:24]=[CH:23][C:22]([CH2:25]C)=[CH:21][CH:20]=3)=[O:17])=[CH:11][CH:10]=2)[CH:3]=1>CN(C=O)C>[NH2:1][C:2]1[N:7]=[CH:6][N:5]=[C:4]([CH2:8][C:9]2[CH:10]=[CH:11][C:12]([NH:15][C:16]([NH:18][C:19]3[CH:20]=[CH:21][C:22]([CH3:25])=[CH:23][CH:24]=3)=[O:17])=[CH:13][CH:14]=2)[CH:3]=1참가 물질
3
실험 절차
The title compound is prepared as described in Example 102 but using 6-(4-aminobenzyl)-pyrimidin-4-ylamine (see Example 157), and DMF as the solvent. The reaction mixture is stirred for 3 h. The title compound is obtained as a white solid: ES-MS: 348.0 [M+H]+; single peak at tR=6.94 min (System 2).
후처리
- customThe title compound is prepared
출처 및 근거
- ORD 기록
- ord-db61654a5b4448e89f12d4369de5083f