Methyl Acrylate → methyl (E)-3-(3-quinolinyl)-2-propenoate

반응식

Br[C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[C:12]([O:16][CH3:17])(=[O:15])[CH:13]=[CH2:14]>>[N:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:11]=[C:2](/[CH:14]=[CH:13]/[C:12]([O:16][CH3:17])=[O:15])[CH:3]=1

참가 물질

반응물 2

HCID 7294Methyl Acrylate

HCID 214133-Bromoquinoline

생성물 1

HCID 1491214methyl (E)-3-(3-quinolinyl)-2-propenoate수율 67%

실험 절차

The title compound was prepared from 3-bromoquinoline (16a) and methyl acrylate using methods as described in the literature for similar compounds (Frank et al., 1978) in 67% yield.

출처 및 근거

ORD 기록: ord-0a312220092941a893271f3d85c088bc
출처 데이터셋: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07652036B2

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