Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → 2-Chloro-5-phenylpyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | 5-phenyl-1H-pyrazin-2-one | HCID 599037 | — |
| 생성물 | 2-Chloro-5-phenylpyrazine | HCID 1236664 | — |
반응 단계
A mixture of 0.01 mol. of 5-phenylpyrazin-2(1H)one 8.0 ml. of POCl3 and a drop of concentrated sulfuric acid is refluxed for 4-5 hr. The solution is poured into 100 g. of ice. The title compound is isolated by filtration and recrystallized.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04402958 |
| 출처 데이터셋 | uspto-grants-1983_09 |
| ORD ID | ord-2130e3284caf45838b838060e626ad40 |
| 출처 메모 | uspto-grants-1983_09 |