Potassium Iodide → HCID 20402707, 화합물

HRID 1995098노트

반응식

HRID 1995098 반응식
[C:1]([C:9]1[C:10]([NH:16][C:17](=[O:20])[CH2:18]Cl)=[CH:11][N:12]([CH3:15])[C:13]=1[CH3:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I-:21].[K+]>C(O)C>[C:1]([C:9]1[C:10]([NH:16][C:17](=[O:20])[CH2:18][I:21])=[CH:11][N:12]([CH3:15])[C:13]=1[CH3:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 4875Potassium IodideHCID 20402708HCID 20402708, 화합물

생성물 1

HCID 20402707HCID 20402707, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

N-(4-benzoyl-1,5-dimethyl(1H)pyrrol-3-yl)2-chloroacetamide (0.741 mole) and potassium iodide (1.62 mole) were refluxed in ethanol (3400 ml) for 5 hours with stirring. The reaction mixture was then cooled, the inorganic salts were filtered off and the solvent was evaporated under vacuum. The obtained residue was purified by washing first with water and then with cold ethanol. M.p. 135°-137° C. Yield 87%.

후처리

  1. temperatureThe reaction mixture was then cooled
  2. filtrationthe inorganic salts were filtered off
  3. customthe solvent was evaporated under vacuum
  4. customThe obtained residue was purified
  5. washby washing first with water

출처 및 근거

ORD 기록
ord-5b0c6240e9054f30a69c9a3fee9ae5b8
출처 데이터셋
uspto-grants-1983_09
특허 번호
US04402970

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