6-Methoxypicolinic acid → HCID 178490499, 화합물

반응식

[CH3:1][O:2][C:3]1[N:8]=[C:7]([C:9]([OH:11])=O)[CH:6]=[CH:5][CH:4]=1.[NH2:12][C:13]1[NH:17][N:16]=[N:15][N:14]=1>>[NH:14]1[C:13]([NH:12][C:9]([C:7]2[CH:6]=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[N:8]=2)=[O:11])=[N:17][N:16]=[N:15]1

참가 물질

반응물 2

HCID 5708916-Methoxypicolinic acid

HCID 178509299HCID 178509299, 화합물

생성물 1

HCID 178490499HCID 178490499, 화합물수율 46.4%

실험 절차

0.48 g of 6-methoxy-2-pyridinecarboxylic acid, 0.51 g of N,N'-carbonyldiimidazole and 0.29 g of 5-aminotetrazole are treated in the same manner as described in Example 2. The crude product thus obtained is recrystallized from a mixture of dimethylformamide, water and ethanol, whereby 0.32 g of N-(5-tetrazolyl)-6-methoxy-2-pyridinecarboxamide is obtained.

후처리

customThe crude product thus obtained
customis recrystallized from a mixture of dimethylformamide, water and ethanol

출처 및 근거

ORD 기록: ord-026878b2fd4c4a278e3344619a644804
출처 데이터셋: uspto-grants-1983_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04404214

반응 노트

불러오는 중…