Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → 2,3,5,6-Tetrafluorobenzyl alcohol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | 2,3,5,6-Tetrafluorobenzoic Acid | HCID 567533 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2,3,5,6-Tetrafluorobenzyl alcohol | HCID 2734029 | 46.7% |
반응 단계
Lithium aluminium hydride (4.6 g) was added in small portions to a stirred solution of 2,3,5,6-tetrafluorobenzoic acid (30.0 g) in dry ether (600 ml) at the ambient temperature, and stirring continued for a period of 3 hours. After decomposition of the excess lithium aluminium hydride with ethyl alcohol, water was added in excess and the ethereal phase separated, washed with water, and concentrated to yield crude 2,3,5,6-tetrafluorobenzyl alcohol (13.0 g) as a colourless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04405640 |
| 출처 데이터셋 | uspto-grants-1983_09 |
| ORD ID | ord-d48cfcf8ff0740429f24171d1e57a511 |
| 출처 메모 | uspto-grants-1983_09 |