Formaldehyde → N-methyl-N-tertiarybutylaminoethoxyethanol
반응식
[C:1]([NH:5][CH2:6][CH2:7][O:8][CH:9]([OH:11])[CH3:10])([CH3:4])([CH3:3])[CH3:2].[CH2:12]=O>[Pd].CO>[CH3:12][N:5]([CH2:6][CH2:7][O:8][CH:9]([OH:11])[CH3:10])[C:1]([CH3:4])([CH3:2])[CH3:3]참가 물질
5
반응 조건
- 온도
- 80 °C
실험 절차
A total of 145 g of tertiarybutylaminoethoxyethanol, 108 g of 37% aqueous formaldehyde, 10 g of 10% Pd/C, and 1 l of methanol were charged to an autoclave, pressured up to 1000 psi with H2 and heated at 80° C. for 8 hours. Filtration and distillation of the reaction mixture yielded 128 g of N-methyl-N-tertiarybutylaminoethoxyethanol with b.p. of 128° C. at 23 mm.
후처리
- filtrationFiltration and distillation of the reaction mixture
출처 및 근거
- ORD 기록
- ord-fe697eead4f6480caab9e00afd11fee4
- 출처 데이터셋
- uspto-grants-1983_09
- 특허 번호
- US04405811
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