Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 7-Benzyl-1-ethoxymethyl-3-methylxanthine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Chloromethyl ethyl ether | HCID 18523 | — |
| 반응물 | 7-Benzyl-3-methylxanthine | HCID 685630 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 7-Benzyl-1-ethoxymethyl-3-methylxanthine | HCID 19689145 | — |
반응 단계
20 g (0.078 mol) of 7-benzyl-3-methylxanthine were stirred at 80° C. for 6 hours with 8.8 g (0.094 mol) of ethoxymethyl chloride and 13 g of potassium carbonate in 500 ml of absolute dimethylformamide, the mixture was filtered and concentrated, and the residue which remained was chromatographed (eluent: dichloromethane/methanol 20:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728686 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-eadaded2a68a4a4683c2b0691e2f1aa0 |
| 출처 메모 | uspto-grants-1998_03 |